Primary Open-Angle Glaucoma and Serum Lipids

  • Suzana Pavljašević Policlinic for Eye Diseases, Public Health Institution Tuzla, Ophthalmology Department, Faculty of Medicine, University of Tuzla
  • Mensura Ašćerić Department of Pharmacology and Toxicology, Faculty of Medicine, University of Tuzla
Keywords: serum lipids, primary open-angle glaucoma, cholesterol, triglyceride

Abstract

The aim of this paper was to prove the relation between serum lipid values (cholesterol, trig- lyceride, low density cholesterol, high density cholesterol and primary open -angle glaucoma. The study includes two patient groups: 50 patients with primary open-angle glaucoma and 50 patients without this disease. However, all 100 patients were tested for serum lipid values. The research covered a period of six months (from May to December 2007.). Primary open-angle glaucoma was diagnosed with intraocular pressure values (between 20,1 and 25,6 mm Hg) measured with Schiotz tonometry. The visual field changes were confirmed with Goldmann perimetry. The gonioscopies were done for diagnosis confirmation. The serum lipid values were confirmed with enzymatic colorimetry in vitro method. U-test (Mann-Witney-Wilcox test) and t-test, as nonparametric tests, were used for statistical evaluations. The cholesterol mean value in the test group was 6,14 mol/dm1 (3,20-8,10 mol/dm3) whereas in the control group it was 5,96 mol/dm3 (2,70-8,80 mol/dm3). U-test was with negative ranks (z=-0,83 AS=0,678). The triglyceride mean value in the test group was 2,38 mol/dm3 (0,84-11,73 mol/m3) and in the control group it was 2,04 mol/dm3 (0,63-5,89 mol/dm3). U-test was with positive ranks (z=0,950 AS=0,342). High density cholesterol was average in the test group with 1,45 mol/dm3 (0,71-3,40 mol/dm3) and in the control group 1,40 mol/m3 (0,80-3,20 mol/dm3). Low density cholesterol in the test group was 3,98 mol/m3 (1,82-6,49 mol/m3) and in the control group 4,08 mol/m3 (2,69-5,69 mol/m3). These results had positive ranks according to U-test. Serum lipid values could be one of predictable factors in primary open-angle glaucoma diagnosis. Due to the patient age, cholesterol values, as common factors in primary open-angle glaucoma and atherosclerosis genesis, could be concern in the same aetiology based on dyslipidaemia as well.

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Primary Open-Angle Glaucoma and Serum Lipids
Published
2009-02-20
How to Cite
1.
Pavljašević S, Ašćerić M. Primary Open-Angle Glaucoma and Serum Lipids. Bosn J of Basic Med Sci [Internet]. 2009Feb.20 [cited 2020Aug.15];9(1):85-8. Available from: http://www.bjbms.org/ojs/index.php/bjbms/article/view/2863
Section
Reviews