Solitary intracranial tuberculoma mimicking a malignant tumor in a patient without tubercular lesions or a history of disease: a case report

  • Javier A. Bustamante-Rengifo Population-Based Cali Cancer Registry, Department of Pathology, School of Medicine, Universidad del Valle Biotechnology and Bacterial Infections Group, Department of Microbiology, Universidad del Valle
  • Luz F. Sua Pathology Unit, Fundación Valle del Lili-Universidad ICESI
  • Miryam Astudillo Biotechnology and Bacterial Infections Group, Department of Microbiology, Universidad del Valle
  • Luis E. Bravo Population-Based Cali Cancer Registry, Department of Pathology, School of Medicine, Universidad del Valle
Keywords: tuberculosis, intracranial tuberculoma, tomography x-ray computed, magnetic resonance imaging, polymerase chain reaction

Abstract

Cerebral tuberculoma is a rare cause of intracranial mass. In Latin America and Colombia where tuberculosis is endemic, it represents between 5 and 30% of brain tumours. A 53-year-old Colombian woman was admitted to a third-level hospital in Cali, Colombia, after reporting loss of consciousness, headache, paresthesia, and flight of ideas for a two-week period. Imaging studies showed a left frontal mass of malignant appearance whose first possible diagnosis was metastatic neoplasia or glioma. With the initial results, absence of history of chronic infectious diseases and a history of thyroidectomy, a surgical procedure was carried out and a histopathological and molecular evaluation was conducted. The pathology report noted necrotizing granulomatous inflammation and tissue staining and molecular tests for detection of M. tuberculosis were positive and the patient was managed with anti-tubercular treatment. Intracranial masses are frequently targeted as a malignant neoplastic disease for surgical treatment. Considering an infectious etiology must be a diagnostic option.

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Solitary intracranial tuberculoma mimicking a malignant tumor in a patient without tubercular lesions or a history of disease: a case report
Published
2013-05-20
How to Cite
1.
Bustamante-Rengifo JA, F. Sua L, Astudillo M, E. Bravo L. Solitary intracranial tuberculoma mimicking a malignant tumor in a patient without tubercular lesions or a history of disease: a case report. Bosn J of Basic Med Sci [Internet]. 2013May20 [cited 2020Jun.2];13(2):129-33. Available from: http://www.bjbms.org/ojs/index.php/bjbms/article/view/2396
Section
Case reports