The Role of the Stroma in Carcinogenesis

  • Nurija Bilalović Department of Clinical Pathology and Cytology, Clinical Center of the University of Sarajevo
  • Semir Vranić Clinical Center of the University of Sarajevo
  • Fadila Serdarević University of South Florida
  • Faris Fočo Department of Maxillofacial Surgery, Clinical Center of the University of Sarajevo
Keywords: carcinogenesis, tumor stroma, cross-talk, stromal fibroblasts

Abstract

This systematic review considers the most recent attitudes and news regarding the influence of the stroma on tumor initiation and progression. It is now widely accepted that tumor stroma plays an active role in carcinogenesis. Many different signaling molecules, ligands and signaling pathways recently have been discovered. This review considers the complexity of interactions between malignant cells and its stroma (cross-talk). The recent advances and better understanding of the tumor-stroma interactions will have important impact on the new and combined therapeutic approaches and modalities.

Downloads

Download data is not yet available.
Published
2006-02-20
How to Cite
1.
Bilalović N, Vranić S, Serdarević F, Fočo F. The Role of the Stroma in Carcinogenesis. Bosn J of Basic Med Sci [Internet]. 2006Feb.20 [cited 2019Sep.22];6(1):33-8. Available from: http://www.bjbms.org/ojs/index.php/bjbms/article/view/3207
Section
Reviews