The Role of the Stroma in Carcinogenesis

Authors

  • Nurija Bilalović Department of Clinical Pathology and Cytology, Clinical Center of the University of Sarajevo
  • Semir Vranić Clinical Center of the University of Sarajevo
  • Fadila Serdarević University of South Florida
  • Faris Fočo Department of Maxillofacial Surgery, Clinical Center of the University of Sarajevo

DOI:

https://doi.org/10.17305/bjbms.2006.3207

Keywords:

carcinogenesis, tumor stroma, cross-talk, stromal fibroblasts

Abstract

This systematic review considers the most recent attitudes and news regarding the influence of the stroma on tumor initiation and progression. It is now widely accepted that tumor stroma plays an active role in carcinogenesis. Many different signaling molecules, ligands and signaling pathways recently have been discovered. This review considers the complexity of interactions between malignant cells and its stroma (cross-talk). The recent advances and better understanding of the tumor-stroma interactions will have important impact on the new and combined therapeutic approaches and modalities.

The Role of the Stroma in Carcinogenesis

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Published

20-02-2006

Issue

Section

Reviews

Categories

How to Cite

1.
The Role of the Stroma in Carcinogenesis. Biomol Biomed [Internet]. 2006 Feb. 20 [cited 2024 Mar. 3];6(1):33-8. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/3207