Epigenetic alterations of the Wnt signaling pathway in cancer: a mini review

Authors

  • Ljiljana Serman Department of Biology, School of Medicine, University of Zagreb
  • Tamara Nikuseva Martic Department of Biology, School of Medicine, University of Zagreb
  • Alan Serman Department of Obstetrics and Gynaecology, Clinical Hospital Sveti Duh, Zagreb, Croatia
  • Semir Vranic Department of Pathology, Clinical Center, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

DOI:

https://doi.org/10.17305/bjbms.2014.4.205

Keywords:

Cancer, epigenetics, Wnt signaling pathway

Abstract

Epigenetic mechanisms play a crucial role in cellular proliferation, migration and differentiation in both normal and neoplastic development. One of the key signaling pathways whose components are altered through the epigenetic mechanisms is the Wnt signaling pathway. In this review, we briefly discuss the key concepts of epigenetics and focus on the recent advances in the Wnt signaling pathway research and its potential diagnostic and therapeutic implications.

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Epigenetic alterations of the Wnt signaling pathway in cancer: a mini review

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Published

12-11-2014

Issue

Vol. 14 No. 4 (2014)

Section

Review

Categories

How to Cite

1.
Epigenetic alterations of the Wnt signaling pathway in cancer: a mini review. Biomol Biomed [Internet]. 2014 Nov. 12 [cited 2025 May 1];14(4):191-4. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/a191
Received 2014-11-01
Accepted 2014-11-02
Published 2014-11-12