Epigenetic alterations of the Wnt signaling pathway in cancer: a mini review

  • Ljiljana Serman Department of Biology, School of Medicine, University of Zagreb
  • Tamara Nikuseva Martic Department of Biology, School of Medicine, University of Zagreb
  • Alan Serman Department of Obstetrics and Gynaecology, Clinical Hospital Sveti Duh, Zagreb, Croatia
  • Semir Vranic Department of Pathology, Clinical Center, University of Sarajevo, Sarajevo, Bosnia and Herzegovina
Keywords: Cancer, epigenetics, Wnt signaling pathway

Abstract

Epigenetic mechanisms play a crucial role in cellular proliferation, migration and differentiation in both normal and neoplastic development. One of the key signaling pathways whose components are altered through the epigenetic mechanisms is the Wnt signaling pathway. In this review, we briefly discuss the key concepts of epigenetics and focus on the recent advances in the Wnt signaling pathway research and its potential diagnostic and therapeutic implications.

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Published
2014-11-12
How to Cite
1.
Serman L, Nikuseva Martic T, Serman A, Vranic S. Epigenetic alterations of the Wnt signaling pathway in cancer: a mini review. Bosn J of Basic Med Sci [Internet]. 2014Nov.12 [cited 2019May20];14(4):191-4. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/a191
Section
Reviews

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