An experimental study on the application of radionuclide imaging in repair of the bone defect

  • Weimin Zhu Department of Sports Medicine, Shenzhen Second People’s Hospital
  • Daping Wang Department of Sports Medicine, Shenzhen Second People’s Hospital
  • Xiaojun Zhang Beijing University of Technology,
  • Wei Lu Department of Sports Medicine, Shenzhen Second People’s Hospital
  • Jianquan Liu Department of Sports Medicine, Shenzhen Second People’s Hospital
  • Liangquan Peng Department of Sports Medicine, Shenzhen Second People’s Hospital
  • Hao Li Department of Sports Medicine, Shenzhen Second People’s Hospital
  • Yun Han Department of Sports Medicine, Shenzhen Second People’s Hospital
  • Yanjun Zeng Beijing University of Technology
Keywords: hydroxyapatite, nanometer, artificial bone, bone defect, radionuclide imaging

Abstract

The aim of our study was to validate the effect of radionuclide imaging in early monitoring of the bone’s reconstruction, the animal model of bone defect was made on the rabbits repaired with HA artificial bone. The ability of bone defect repair was evaluated by using radionuclide bone imaging at 2, 4, 8 and 12 weeks postoperatively. The results indicate that the experimental group stimulated more bone formation than that of the control group. The differences of the bone reconstruction ability were statistically significant (p<0.05). The nano-HA artificial has good bone conduction, and it can be used for the treatment of bone defects. Radionuclide imaging may be an effective and first choice method for the early monitoring of the bone’s reconstruction.

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Published
2011-08-20
How to Cite
1.
Zhu W, Wang D, Zhang X, Lu W, Liu J, Peng L, Li H, Han Y, Zeng Y. An experimental study on the application of radionuclide imaging in repair of the bone defect. Bosn J of Basic Med Sci [Internet]. 2011Aug.20 [cited 2019Mar.24];11(3):163-8. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/2568
Section
Biomaterials