Angiosarcoma of the ovary in an 11 year old girl: Case report and review of the literature

  • Ermina Iljazović Department of Pathology, University Clinical Center Tuzla
  • Snježana Tomić Department of Pathology, Clinical Center Split
  • Jasminka Mustedanagić-Mujanović Department of Pathology, University Clinical Center Tuzla
  • Zinaida Karasalihović Department of Pathology, University Clinical Center Tuzla
  • Majda Kuljanin Department of Pathology, University Clinical Center Tuzla
  • Zlatan Fatušić Department of Gynecology and Obstetrics, University Clinical Center Tuzla
  • Elvira Konjić Pediatric Clinic, University Clinical Center Tuzla
  • Edin Husarić Pediatric Clinic, University Clinical Center Tuzla
  • Amila Latifagić Pediatric Clinic, University Clinical Center Tuzla
  • Lejla Arnautalić Clinic for Radiology and Nuclear Medicine, University Clinical Center Tuzla
Keywords: primary angiosarcoma, ovary, childhood

Abstract

Sarcomas of the female genital tract in general are rare and ovarian sarcomas comprise less than 1% of ovarian malignancies. In the literature there are 15 reported angiosarcomas of patients 21 year old and younger with no one originated in the ovary. We report a case of ovarian angiosarcoma in an 11 year old girl, presented with left side hip pain. MRI of abdomen and pelvis confirmed expansive solid and cystic mass occupied both ovaries. Imunohistochemistry staining was performed, CD34, Factor VIII, CD31, in order to confirm the diagnosis. Final diagnosis was angiosarcoma. The patient received 6 cycles of chemotherapy, according to the CWS-2002P protocol. 8 months after the diagnosis was established, there were no signs of any tumors according to the ultrasound, CT scan, and MRI. Although, extremely rare, angiosarcoma can also affect children and this diagnosis should be considered carefully in tumor with rich vascular network, necrosis and brisk mitotic activity

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Published
2011-05-20
How to Cite
1.
Iljazović E, Tomić S, Mustedanagić-Mujanović J, Karasalihović Z, Kuljanin M, Fatušić Z, Konjić E, Husarić E, Latifagić A, Arnautalić L. Angiosarcoma of the ovary in an 11 year old girl: Case report and review of the literature. BJBMS [Internet]. 20May2011 [cited 22Mar.2019];11(2):132-6. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/2599
Section
Case reports