The Mechanism of Protracted Wound Healing on Oral Mucosa in Diabetes. Review

  • Yoshihiro Abiko Department of Dental Science, Division of Oral Medicine and Pathology, Institute of Personalized Medical Science, Health Sciences University of Hokkaido
  • Denis Selimovic Department of Oral Medicine and Surgery, University Hospitals of Strasbourg, 1, Place de l’Hopital and Institute National de la Santé et Recherche Medicale (INSERM U977)
Keywords: Diabetes, oral mucosa wound healing

Abstract

Diabetic patients increase their body’s susceptibility to infection and diabetes is a risk factor for periodontal diseases and oral infection. Although many studies showed the mechanism of impaired wound healing in diabetes, there are still arguments to shed light on what kind of factors, including local and systemic factors are involved in the protracted wound healing. This review article summarizes reports on the wound healing in diabetes and discusses the mechanism of the protracted wound healing of the oral mucosa in diabetes. Delayed vascularization, reduction in blood flow, decline in innate immunity, decreases in growth factor production, and psychological stresses may be involved in the protracted wound healing of the oral mucosa in diabetics.

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The Mechanism of Protracted Wound Healing on Oral Mucosa in Diabetes. Review
Published
2010-08-20
How to Cite
1.
Abiko Y, Selimovic D. The Mechanism of Protracted Wound Healing on Oral Mucosa in Diabetes. Review. Bosn J of Basic Med Sci [Internet]. 2010Aug.20 [cited 2020Sep.25];10(3):186-91. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/2683
Section
Reviews