Immunosuppressive Therapy Protocols in Kidney Transplantation in Adults

  • Jasenko Karamehić Institute of Clinical Immunology, Sarajevo University Clinics Centre
  • Marc Lorber The Yale University School of Medicine-Department of Organ Transplantation
  • Richard Formica The Yale University School of Medicine-Department of Organ Transplantation
  • Faris Gavrankapetanović Institute of Clinical Immunology, Sarajevo University Clinics Centre
  • Bećir Heljić Department of Endocrinology, Sarajevo University Clinics Centre
  • Đemo Subašić Institute of Clinical Immunology, Sarajevo University Clinics Centre
  • Lamija Zečević Institute of Clinical Immunology, Sarajevo University Clinics Centre
Keywords: drug, immunosuppression, kidney transplant

Abstract

In practical terms, regardless of HLA compatibility level, whenever tissues are transplanted from one person to another it is essential to suppress the immune response of the recipient. A variety of methods are available however, the most frequently used ones have the disadvantage of being immunologicaly non specific. The consequence is a difficult balance between immunosuppression sufficient to prevent the tissue rejection and maintenance of immune system at the level of ability to adequately deal with an infection. The goal, not yet achieved, is to find a way of generating donor specific immunosuppression that leaves the immune machinery otherwise completely intact. The major approaches to immunosuppression are described below.

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Immunosuppressive Therapy Protocols in Kidney Transplantation in Adults
Published
2006-08-20
How to Cite
1.
Karamehić J, Lorber M, Formica R, Gavrankapetanović F, Heljić B, Subašić Đemo, Zečević L. Immunosuppressive Therapy Protocols in Kidney Transplantation in Adults. Bosn J of Basic Med Sci [Internet]. 2006Aug.20 [cited 2020Sep.25];6(3):43-7. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/3143
Section
Reviews