Mitochondrial medicine - a key to solve pathophysiology of 21 century diseases

Authors

  • Emina Kiseljaković Institute for Physiology and Biochemistry, Department of Biochemistry, Faculty of Medicine
  • Radivoj Jadrić Institute for Physiology and Biochemistry, Department of Biochemistry, Faculty of Medicine
  • Sabaheta Hasić Institute for Physiology and Biochemistry, Department of Biochemistry, Faculty of Medicine
  • Lorenka Ljuboja Institute for Physiology and Biochemistry, Department of Biochemistry, Faculty of Medicine
  • Jovo Radovanović Institute for Physiology and Biochemistry, Department of Biochemistry, Faculty of Medicine
  • Husein Kulenović Institute for Physiology and Biochemistry, Department of Biochemistry, Faculty of Medicine
  • Mira Winterhalter-Jadrić Institute for Physiology and Biochemistry, Department of Biochemistry, Faculty of Medicine

DOI:

https://doi.org/10.17305/bjbms.2002.3580

Keywords:

mitochondria, mtDNA, mitochondrial diseases

Abstract

Over the past 13 years mitochondrial defects have been involved in wide variety of degenerative diseases - Parkinson disease, Alzheimer dementia, arteriosclerosis, ageing and cancer. Mitochondria are believed to control apoptosis or programmed cell death. Disturbance in mitochondrial metabolism has also been implicated in many common diseases such as congestive hart failure, diabetes and migraine. Scientific investigations have showed complexities in mitochondrial genetics, but at the same time, pathophysiology of mitochondrial diseases is still enigma. Mitochondria and their DNAs are opening the era of "mitochondrial medicine". What we today call "a mitochondrial medicine" is only a part of the whole panorama of diseases based on disordered mitochondrial function.

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Mitochondrial medicine - a key to solve pathophysiology of 21 century diseases

Published

20-02-2008

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How to Cite

1.
Mitochondrial medicine - a key to solve pathophysiology of 21 century diseases. Biomol Biomed [Internet]. 2008 Feb. 20 [cited 2024 May 19];2(1-2):46-8. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/3580