Decreased heart rate recovery may predict a high SYNTAX score in patients with stable coronary artery disease

Authors

  • Sadık Volkan Emren Department of Cardiology, Katip Celebi University School of Medicine, Izmir, Turkey
  • Rahman Bilal Gediz Department of Cardiology, Manisa State Hospital, Manisa, Turkey
  • Oktay Şenöz Department of Cardiology, Çiğli State Hospital, Izmir, Turkey
  • Uğur Karagöz Department of Cardiology, Katip Celebi University School of Medicine, Izmir, Turkey
  • Ersin Çağrı Şimşek Department of Cardiology, Tepecik Training and Education Hospital, Izmir, Turkey
  • Fatih Levent Department of Cardiology, Tınaztepe Hospital, Izmir, Turkey
  • Emre Özdemir Department of Cardiology, Katip Celebi University School of Medicine, Izmir, Turkey
  • Mustafa Ozan Gürsoy Department of Cardiology, Katip Celebi University School of Medicine, Izmir, Turkey
  • Cem Nazlı Department of Cardiology, Katip Celebi University School of Medicine, Izmir, Turkey

DOI:

https://doi.org/10.17305/bjbms.2019.3725

Keywords:

Heart rate recovery, SYNTAX score, coronary artery disease, CAD, HRR

Abstract

An impaired heart rate recovery (HRR) has been associated with increased risk of cardiovascular events, cardiovascular, and all‐cause mortality. However, the diagnostic ability of HRR for the presence and severity of coronary artery disease (CAD) has not been clearly elucidated. Our aim was to investigate the relationship between HRR and the SYNTAX (SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery) score in patients with stable CAD (SCAD). A total of 406 patients with an abnormal treadmill exercise test and ≥50% coronary stenosis on coronary angiography were included. The HRR was calculated by subtracting the HR in the first minute of the recovery period from the maximum HR during exercise. The SYNTAX score ≥23 was accepted as high. Correlation of HRR with SYNTAX score and independent predictors of high SYNTAX score were determined. A high SYNTAX score was present in 172 (42%) patients. Mean HRR was lower in patients with a high SYNTAX score (9.8 ± 4.5 vs. 21.3 ± 9, p < 0.001). The SYNTAX score was negatively correlated with HRR (r: -0.580, p < 0.001). In multivariate logistic regression analysis, peripheral arterial disease (OR: 13.3; 95% CI: 3.120–34.520; p < 0.001), decreased HRR (OR: 0.780; 95% CI: 0.674–0.902; p = 0.001), peak systolic blood pressure (OR: 1.054; 95% CI: 1.023–1.087; p = 0.001), and peak HR (OR: 0.950; 95% CI: 0.923–0.977; p < 0.001) were found to be independent predictors of a high SYNTAX score. Our results showed that HRR is significantly correlated with the SYNTAX score, and a decreased HRR is an independent predictor of a high SYNTAX score in patients with SCAD.

Author Biographies

  • Sadık Volkan Emren, Department of Cardiology, Katip Celebi University School of Medicine, Izmir, Turkey
    Department of Cardiology
  • Rahman Bilal Gediz, Department of Cardiology, Manisa State Hospital, Manisa, Turkey
    Department of Cardiology
  • Oktay Şenöz, Department of Cardiology, Çiğli State Hospital, Izmir, Turkey
    Department of Cardiology
  • Uğur Karagöz, Department of Cardiology, Katip Celebi University School of Medicine, Izmir, Turkey
    Department of Cardiology
  • Ersin Çağrı Şimşek, Department of Cardiology, Tepecik Training and Education Hospital, Izmir, Turkey
    Department of Cardiology
  • Fatih Levent, Department of Cardiology, Tınaztepe Hospital, Izmir, Turkey
    Department of Cardiology
  • Emre Özdemir, Department of Cardiology, Katip Celebi University School of Medicine, Izmir, Turkey
    Department of Cardiology
  • Mustafa Ozan Gürsoy, Department of Cardiology, Katip Celebi University School of Medicine, Izmir, Turkey
    Department of Cardiology
  • Cem Nazlı, Department of Cardiology, Katip Celebi University School of Medicine, Izmir, Turkey
    Department of Cardiology
Decreased heart rate recovery may predict a high SYNTAX score in patients with stable coronary artery disease

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Published

12-02-2019

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Section

Translational and Clinical Research

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How to Cite

1.
Decreased heart rate recovery may predict a high SYNTAX score in patients with stable coronary artery disease. Biomol Biomed [Internet]. 2019 Feb. 12 [cited 2024 Mar. 19];19(1):109-15. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/3725