An insight into osteoarthritis susceptibility: Integration of immunological and genetic background

Keywords: osteoarthritis, immunology, genetic polymorphisms, genetic susceptibility

Abstract

Osteoarthritis (OA) is a progressive degenerative disease that affects all synovial joints, causing the disability of the main locomotor diarthrodial joints. OA pathogenesis is caused by a complex interplay between a number of genetic and environmental risk factors, involved in the early onset and progression of this chronic inflammatory joint disease. Uncovering the underlying immunological and genetic mechanisms will enable an insight into OA pathophysiology and lead to novel and integrative approaches in the treatment of OA patients, together with a reduction of the disease risk, or a delay of its onset in susceptible patients.

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An insight into osteoarthritis susceptibility: Integration of immunological and genetic background
Published
2020-09-11
How to Cite
1.
Stefik D, Vranic V, Ivkovic N, Abazovic D, Maric D, Vojvodic D, Supic G. An insight into osteoarthritis susceptibility: Integration of immunological and genetic background. Bosn J of Basic Med Sci [Internet]. 2020Sep.11 [cited 2020Oct.1];. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/4735
Section
Immunology