Clinical management of chronic mercury intoxication secondary to skin lightening products: A proposed algorithm

Authors

  • Fitri Fareez Ramli Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia https://orcid.org/0000-0003-4030-7616

DOI:

https://doi.org/10.17305/bjbms.2020.4759

Keywords:

Mercury, cosmetics, skin-lightening, skin-whitening, bleaching, nephrotic syndrome, neuropsychiatry, dementia

Abstract

Mercury is a toxic substance that is commonly used in skin lightening products. Various effects on humans have been observed, which affect both users and non-users. Many studies reported delayed diagnosis and treatment, even after weeks of hospitalization. The possible reasons are non-specific clinical manifestation and lack of awareness and knowledge regarding chronic mercury intoxication secondary to skin lightening products. A thorough history of mercury exposure is crucial. Physical assessment and relevant supporting tests are indicated to establish a diagnosis. Blood and urine mercury levels are an essential examination for diagnosis and monitoring of the progress and response to treatment. The primary treatment is the discontinuation of the skin lightening products. Chelation therapy is not mandatory and is usually indicated for symptomatic patients. The prognosis depends on the duration of the product use, concentration of mercury in the skin product, and the severity of clinical presentation.

Clinical management of chronic mercury intoxication secondary to skin lightening products: A proposed algorithm

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Published

01-06-2021

How to Cite

1.
Clinical management of chronic mercury intoxication secondary to skin lightening products: A proposed algorithm. Biomol Biomed [Internet]. 2021 Jun. 1 [cited 2024 Mar. 5];21(3):261-9. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/4759