Extent of clinical attachment loss as a practical parameter in efficacy of adjunctive photodynamic therapy in stage II - IV grade C Periodontitis (Aggressive periodontitis): A systematic review and meta-analysis

Authors

  • Zahra Baghani Department of Periodontics, Faculty of Dentistry, Sabzevar University of Medical Sciences, Sabzevar, Iran https://orcid.org/0000-0003-0847-7076
  • Samira Basir Shabestari Department of Oral Medicine, Firoozgar Hospital, Iran University of Medical Sciences,Tehran, Iran
  • Malihe Karrabi Department of Periodontics, Faculty of Dentistry, Sabzevar University of Medical Sciences, Sabzevar, Iran https://orcid.org/0000-0002-8711-8823

DOI:

https://doi.org/10.17305/bjbms.2022.7157

Keywords:

Aggressive periodontitis, Attachment loss, Photo chemotherapy, Periodontal debridement, Dental scaling, Therapy

Abstract

This systematic review and meta-analysis aimed to assess the extent of clinical attachment loss (CAL) as a clinical parameter in the efficacy of antimicrobial photodynamic therapy (aPDT) in non-surgical management of stage II-IV grade C molar-incisor pattern Periodontitis. This review protocol was conducted in accordance with PRISMA statements and is registered in PROSPERO (CRD42022321211). An electronic and manual search was conducted for relevant articles comparing the efficacy of aPDT versus scaling and root planning (SRP) alone or with amoxicillin/metronidazole (AMX/MET) published up until December 2021. The mean clinical attachment loss (CAL), probing depth (PD) reduction, and bleeding on probing (BOP) with a 95% confidence interval (CI) were pooled and compared between the two groups with CAL < and > 7 mm using a random-effect model after 3 and 6 months. To assess the heterogeneity of the findings, the I2 test was applied and Publication bias was evaluated by visual examination of the funnel plot symmetry. Analysis of 9 studies indicated a significant difference in clinical attachment gain in patients with CAL > 7 mm between the aPDT group and the SRP alone (mean difference=0.92, 95% CI=0.01-1.84, P=0.05) and SRP + AMX/MET (mean difference=0.91, 95% CI=-0.14-1.68, P=0.02) control groups. However, this difference was not significant in patients with CAL < 7 mm. Despite the limitations of the included studies, aPDT can be suggested for the improvement of clinical parameters in grade C molar-incisor pattern Periodontitis with CAL > 7 mm. However, its application in milder cases requires further investigation.

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The extent of clinical attachment loss as a clinical parameter in the efficacy of adjunctive antimicrobial photodynamic therapy in stage II-IV grade C molar-incisor pattern Periodontitis: A systematic review and meta-analysis

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Published

2022-05-29

How to Cite

1.
Baghani Z, Basir Shabestari S, Karrabi M. Extent of clinical attachment loss as a practical parameter in efficacy of adjunctive photodynamic therapy in stage II - IV grade C Periodontitis (Aggressive periodontitis): A systematic review and meta-analysis. Bosn J of Basic Med Sci [Internet]. 2022May29 [cited 2022Jul.5];. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/7157

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Section

Reviews