Basic principles of drug--excipients interactions

Authors

  • Edina Vranić Department of Pharmaceutical Technology, University of Sarajevo, Faculty of Pharmacy, Sarajevo, Bosnia and Herzegovina

DOI:

https://doi.org/10.17305/bjbms.2004.3421

Keywords:

excipient, drug, interaction

Abstract

Excipients are generally considered inert additives included in drug formulation to help in the manufacturing, administration or absorption. Other reasons for inclusion concern product differentiation, appearance enhancement or retention of quality. Excipients can initiate, propagate or participate in chemical or physical interactions with an active substance, possibly leading to compromised quality or performance of the medication. Understanding the chemical and physical nature of excipients, the impurities or residues associated with them and how they may interact with other materials, or with each other, forewarns the pharmaceutical technologist of possibilities for undesirable developments.

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Basic principles of drug--excipients interactions

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Published

20-05-2004

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Section

Reviews

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How to Cite

1.
Basic principles of drug--excipients interactions. Biomol Biomed [Internet]. 2004 May 20 [cited 2024 May 23];4(2):56-8. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/3421