Pharmacology

199 Items

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Integrating bioinformatics and experimental models to investigate the mechanism of the chelidonine-induced mitotic catastrophe via the AKT/FOXO3/FOXM1 axis in breast cancer cells

Huimin Li, Xiyu Tang, Zhiwei Sun, Zhongyuan Qu, Xiang Zou
Effects of the CB1 receptor antagonists AM6545 and AM4113 on metabolic syndrome-induced prostatic hyperplasia in rats

Basma G. Eid, Thikryat Neamatallah, Lenah S. Binmahfouz, Amina M. Bagher, Abdulmohsin J. Alamoudi, Hibah Mubarak Aldawsari, Abeer Hanafy, Atif Hasan, Hany M. El-Bassossy, Ashraf B. Abdel-Naim, Kiran Vemuri, Alexandros Makriyannis

1069–1078
Exogenous spermidine alleviates diabetic cardiomyopathy via suppressing reactive oxygen species, endoplasmic reticulum stress, and Pannexin-1-mediated ferroptosis

Jian Sun, Jiyu Xu, Yong Liu, Yitong Lin, Fengge Wang, Yue Han, Shumin Zhang, Xiaoyan Gao, Changqing Xu, Hui Yuan

825–837
Hepatoprotective effect of taxifolin on cyclophosphamide-induced oxidative stress, inflammation, and apoptosis in mice: Involvement of Nrf2/HO-1 signaling

Osama Y. Althunibat, Mohammad H. Abukhalil, Muthana M. Jghef , Manal A. Alfwuaires, Abdulmohsen I. Algefare, Bader Alsuwayt, Reem Alazragi, Mohammed A. S. Abourehab, Afaf F. Almuqati, Shaik Karimulla, Saleem H. Aladaileh

649–660
Sivelestat sodium attenuates acute lung injury by inhibiting JNK/NF-κB and activating Nrf2/HO-1 signaling pathways

Hong Zhang, Jun Zeng, Jiankang Li, Huankai Gong, Meiling Chen, Quan Li, Shengxing Liu, Shanjun Luo, Huanxiang Dong, Yingke Xu, Huanling Duan, Ling Haung, Chuanzhu Lv

457–470
Evolution of the combined effect of different irrigation solutions and activation techniques on the removal of smear layer and dentin microhardness in oval-shaped root canal: An in-vitro study

Lu Shi, Jie Wan, Yunfei Yang, Ying Yao, Ruiming Yang, Wen Xie

126-136
The α7 nicotinic acetylcholine receptor agonist PNU-282987 ameliorates sepsis-induced acute kidney injury through CD4+CD25+ regulatory T cells in rats

Xiaocui Shi, Juncong Li, Yuzhen Han, Jingyi Wang, Qingping Li, Yue Zheng, Wenxiong Li

882-893
IC50: an unsuitable measure for large-sized prostate cancer spheroids in drug sensitivity evaluation

Yipeng Xu, Gabriela Pachnikova, He Wang, Yaoyao Wu, Dorothea Przybilla, Reinhold Schäfer, Zihao Chen, Shaoxing Zhu, Ulrich Keilholz

580-592
Regulatory aspects of biological medicines in Bosnia and Herzegovina

Biljana Tubić, Saša Jungić

511-522
Tenofovir-silver nanoparticles conjugate ameliorates neurocognitive disorders and protects ultrastructural and cytoarchitectonic properties of the prefrontal cortex in diabetic rats

Sodiq Lawal, Olojede Samuel, Sheu Oluwadare Sulaiman, Okikioluwa Stephen Aladeyelu, Roshila Moodley, Edwin C. Stephen Naidu , Carmen Olivia Rennie, Onyemaechi Okpara Azu

569-579
Effect of bisoprolol on central aortic systolic pressure in Chinese hypertensive patients after the initial dose and long-term treatment

Weiwei Zeng, Brian Tomlinson

427-434
Application of microfluidic chips in anticancer drug screening

Xin-yue Fan, Zhuo-fen Deng, Yan-yan Yan, Valerii E. Orel, Andrii Shypko, Valerii B. Orel, Donika Ivanova, Christian Pilarsky, Jing Tang, Zhe-Sheng Chen, Jian-ye Zhang

302-314
Resveratrol ameliorates neuronal apoptosis and cognitive impairment by activating the SIRT1/RhoA pathway in rats after anesthesia with sevoflurane

Qiaoyun Zhou, Yingfeng Deng, Xuelian Hu, Yinye Xu

110-117
An insight into lung cancer: a comprehensive review exploring ALK TKI and mechanisms of resistance

Adela Patcas, Ana Florica Chis, Claudia Florentina Militaru, Ioana Roxana Bordea, Ruxandra Rajnoveanu, Ovidiu Florin Coza, Reem Hanna, Tamas Tiberiu, Doina Adina Todea

1-13
Pharmacogenetics of new classes of antidiabetic drugs

Selma Imamovic Kadric, Aida Kulo Cesic, Tanja Dujic

659-671
MPTP-induced mouse model of Parkinson’s disease: A promising direction of therapeutic strategies

Musa Mustapha, Che Norma Mat Taib

422-433
Raloxifene inhibits the overexpression of TGF-β1 in cartilage and regulates the metabolism of subchondral bone in rats with osteoporotic osteoarthritis

Shao-Hua Ping, Fa-Ming Tian, Hao Liu , Qi Sun, Li-Tao Shao, Qiang-Qiang Lian, Liu Zhang

284-293
Combined inhibition of ACK1 and AKT shows potential toward targeted therapy against KRAS-mutant non-small-cell lung cancer

Xiangjing Yu, Jie Liu, Huawei Qiu, Huiting Hao, Jinhong Zhu, Shiyun Peng

198-207
Pharmacogenomics biomarkers for personalized methadone maintenance treatment: The mechanism and its potential use

Fitri Fareez Ramli

145-154
Targeting HER2 expression in cancer: New drugs and new indications

Semir Vranić, Semir Bešlija, Zoran Gatalica

1-4

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