Pharmacology

207 Items

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The cardiac toxicity of PAMAM dendrimer drug delivery systems can be attenuated with the adjunct use of cardioprotective agents

Saghir Akhtar, Fawzi Babiker, Aisha Al-Kouh, Ibrahim F Benter

914–924
Piperine inhibits the proliferation of colorectal adenocarcinoma by regulating ARL3-mediated endoplasmic reticulum stress

Chenqu Wu, Yanqing Qian, Jun Jiang, Deming Li, Li Feng

391–405
Synthesis, characterization, and in vitro–in ovo toxicological screening of silibinin fatty acids conjugates as prodrugs with potential biomedical applications

Cristina Dehelean, Ersilia Alexa, Iasmina Marcovici, Andrada Iftode, Geza Lazar, Andrea Simion, Vasile Chis, Adrian Pirnau, Simona Cinta Pinzaru, Estera Boeriu

1735–1750
Preparation, characterization, and in vitro cytogenotoxic evaluation of a novel dimenhydrinate-β-cyclodextrin inclusion complex

Lamija Hindija, Jasmina Hadžiabdić, Anja Haverić, Ognjenka Rahić, Maida Hadžić Omanović, Lejla Čaluk Klačar, Irma Durmišević, Amina Tucak Smajić, Merima Šahinović, Edina Vranić

1637–1650
Puerarin alleviates osteoporosis in rats by targeting the JAK2/STAT3 signaling pathway

Xinlei Zhao, Jiaxuan Zhou, Yanqing Liu, Jianguo Wang, Youcai Liu, Beiyu Wang, Caiting Han, Shengjie Zhao, Yijun Zhang

1651–1661
Quercetin alleviates liver fibrosis via regulating glycolysis of liver sinusoidal endothelial cells and neutrophil infiltration

Xiaoying Chen, Yifan Wang, Jie Wan, Xiaoyun Dou, Chuzhao Zhang, Meng Sun, Fang Ye

1806–1815
Echinacoside ameliorates hepatic fibrosis and tumor invasion in rats with thioacetamide-induced hepatocellular carcinoma

Ajwan Z Albalawi, Areej S Alatawi, Shekha M Al-Atwi, Lama S Alhwyty, Kadi M Alharbi, Shahad A Alshehri, Wasayf A Almarwani, Khulud K Aljohani, Hanan M Hassan, Mohammed M H Al-Gayyar

1186–1198
Integrating bioinformatics and experimental models to investigate the mechanism of the chelidonine-induced mitotic catastrophe via the AKT/FOXO3/FOXM1 axis in breast cancer cells

Huimin Li, Xiyu Tang, Zhiwei Sun, Zhongyuan Qu, Xiang Zou

560–574
Effects of neratinib on angiogenesis and the early stage of the embryo using chicken embryo as a model

Hadeel Kheraldine, Arij Fouzat Hassan, Hashim Alhussain, Hamda Al-Thawadi, Semir Vranic, Ala-Eddin Al Moustafa

575–581
Effects of the CB1 receptor antagonists AM6545 and AM4113 on metabolic syndrome-induced prostatic hyperplasia in rats

Basma G. Eid, Thikryat Neamatallah, Lenah S. Binmahfouz, Amina M. Bagher, Abdulmohsin J. Alamoudi, Hibah Mubarak Aldawsari, Abeer Hanafy, Atif Hasan, Hany M. El-Bassossy, Ashraf B. Abdel-Naim, Kiran Vemuri, Alexandros Makriyannis

1069–1078
Exogenous spermidine alleviates diabetic cardiomyopathy via suppressing reactive oxygen species, endoplasmic reticulum stress, and Pannexin-1-mediated ferroptosis

Jian Sun, Jiyu Xu, Yong Liu, Yitong Lin, Fengge Wang, Yue Han, Shumin Zhang, Xiaoyan Gao, Changqing Xu, Hui Yuan

825–837
Hepatoprotective effect of taxifolin on cyclophosphamide-induced oxidative stress, inflammation, and apoptosis in mice: Involvement of Nrf2/HO-1 signaling

Osama Y. Althunibat, Mohammad H. Abukhalil, Muthana M. Jghef , Manal A. Alfwuaires, Abdulmohsen I. Algefare, Bader Alsuwayt, Reem Alazragi, Mohammed A. S. Abourehab, Afaf F. Almuqati, Shaik Karimulla, Saleem H. Aladaileh

649–660
Sivelestat sodium attenuates acute lung injury by inhibiting JNK/NF-κB and activating Nrf2/HO-1 signaling pathways

Hong Zhang, Jun Zeng, Jiankang Li, Huankai Gong, Meiling Chen, Quan Li, Shengxing Liu, Shanjun Luo, Huanxiang Dong, Yingke Xu, Huanling Duan, Ling Haung, Chuanzhu Lv

457–470
Evolution of the combined effect of different irrigation solutions and activation techniques on the removal of smear layer and dentin microhardness in oval-shaped root canal: An in-vitro study

Lu Shi, Jie Wan, Yunfei Yang, Ying Yao, Ruiming Yang, Wen Xie

126-136
The α7 nicotinic acetylcholine receptor agonist PNU-282987 ameliorates sepsis-induced acute kidney injury through CD4+CD25+ regulatory T cells in rats

Xiaocui Shi, Juncong Li, Yuzhen Han, Jingyi Wang, Qingping Li, Yue Zheng, Wenxiong Li

882-893
IC50: an unsuitable measure for large-sized prostate cancer spheroids in drug sensitivity evaluation

Yipeng Xu, Gabriela Pachnikova, He Wang, Yaoyao Wu, Dorothea Przybilla, Reinhold Schäfer, Zihao Chen, Shaoxing Zhu, Ulrich Keilholz

580-592
Regulatory aspects of biological medicines in Bosnia and Herzegovina

Biljana Tubić, Saša Jungić

511-522
Tenofovir-silver nanoparticles conjugate ameliorates neurocognitive disorders and protects ultrastructural and cytoarchitectonic properties of the prefrontal cortex in diabetic rats

Sodiq Lawal, Olojede Samuel, Sheu Oluwadare Sulaiman, Okikioluwa Stephen Aladeyelu, Roshila Moodley, Edwin C. Stephen Naidu , Carmen Olivia Rennie, Onyemaechi Okpara Azu

569-579
Application of microfluidic chips in anticancer drug screening

Xin-yue Fan, Zhuo-fen Deng, Yan-yan Yan, Valerii E. Orel, Andrii Shypko, Valerii B. Orel, Donika Ivanova, Christian Pilarsky, Jing Tang, Zhe-Sheng Chen, Jian-ye Zhang

302-314
Effect of bisoprolol on central aortic systolic pressure in Chinese hypertensive patients after the initial dose and long-term treatment

Weiwei Zeng, Brian Tomlinson

427-434

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