Sertraline and Alprazolam in the Treatment of Panic Disorder

Authors

  • Saida Fišeković Psychiatric Clinic, University Clinics Center
  • Svjetlana Loga-Zec Institute for Pharmacology, Clinical Pharmacology and Toxicology, School of Medicine

DOI:

https://doi.org/10.17305/bjbms.2005.3292

Keywords:

panic disorders, SSRI, benzodiazepine

Abstract

A compared, 12 week, placebo controlled study, with fixed dose, outpatient study of patients diagnosed with panic disorder with and without agoraphobia according to ICD-10, was conducted to evaluate the efficacy and safety of sertraline and alprazolam. The study included 40 patients, divided in two groups. We evaluated number of ICD-10-defined panic attacks, agoraphobia and anticipatory anxiety. All patients were aged 18 year and older and were randomized to either sertraline or alprazolam. Sertraline applied in fixed doses of 20 mg/day and alprazolam in doses 1-1,5 mg/day significantly reduced the frequency of panic attacks in panic disorder patients, reduced symptoms of agoraphobia and anticipatory anxiety

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Sertraline and Alprazolam in the Treatment of Panic Disorder

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Published

20-05-2005

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Section

Translational and Clinical Research

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How to Cite

1.
Sertraline and Alprazolam in the Treatment of Panic Disorder. Biomol Biomed [Internet]. 2005 May 20 [cited 2024 May 19];5(2):78-81. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/3292