Complementarity of Standard Cytogenetic Assays

  • Slavka Ibrulj Faculty of Medicine, University of Sarajevo Institute for Genetic Engineering and Biotechnology
  • Sanin Haverić Institute for Genetic Engineering and Biotechnology
  • Anja Haverić Institute for Genetic Engineering and Biotechnology
Keywords: lymphocytes culture, micronuclei, chromosome aberrations

Abstract

Standard cytogenetic assays used in genotoxicology usually include chromosome aberrations analysis and micronucleus cytokinesis-block assay. Both tests originate on standard protocol for lymphocyte culture and can be used as complement or substitute to each other. Aim of this study was to evaluate complementarities between results of chromosome aberration analysis assay and results of micronucleus cytokinesis-block assay in representative sample of inhabitants from Bosnia and Herzegovina. The aim was achieved by calculating Pearson correlation coefficient and simple linear regression.

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Complementarity of Standard Cytogenetic Assays
Published
2008-02-20
How to Cite
1.
Ibrulj S, Haverić S, Haverić A. Complementarity of Standard Cytogenetic Assays. Bosn J of Basic Med Sci [Internet]. 2008Feb.20 [cited 2020Dec.5];8(1):34-7. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/2992
Section
Molecular Biology