Management of Chronic Nonbacterial Prostatitis/Chronic Pelvic Pain Syndrome

  • Benjamin Kulovac Urology Clinic, University of Sarajevo Clinics Centre
  • Damir Aganović Urology Clinic, University of Sarajevo Clinics Centre
  • Alden Prcić Urology Clinic, University of Sarajevo Clinics Centre
  • Osman Hadžiosmanović Urology Clinic, University of Sarajevo Clinics Centre
Keywords: chronic nonbacterial prostatitis/chronic pelvic pain syndrome, therapy

Abstract

Chronic nonbacterial prostatitis/chronic pelvic pain syndrome is unsatisfactorily defined and insufficiently studied illness. Also, the treatment success is questionable and therefore, this illness is a therapeutical problem for urologists - which medications are the best choice in treating this uncomfortable condition?

This paper presents results of prospective, open, analytical, comparative study that was performed on 90 patients with diagnosed chronic nonbacterial prostatitis/chronic pelvic pain syndrome. Patients were divided into three groups and were treated with two medications ciprofloxacin (C), doxazosin (D) and combination of ciprofloxacin + doxazosin (C+D). The effects were measured using symptom questionnaire for prostate illnesses of the National Institute for Health - USA (NIH-CPSI). During the basic evaluation, sum ranging from 0 to 43 was calculated for each patient. This number is called total sum NIH-CPSI (National Institutes of Health Chronic Prostatitis Symptom Index) of the questionnaire, which generates the questions from 1 to 9.

The most significant change occurred in C+D group where the total sum changed from 18-38 in the beginning to 5-31 at the end of the treatment (55,1% (p<0,001)). Significant changes were also found in D group where the change was 46, 4% (p<0,001). At the end of the treatment no significant change was registered in C group (p<0,005): p<0,001 – significance threshold. Combination of ciprofloxacin + doxazosin proved to be the best choice for treatment.

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Management of Chronic Nonbacterial Prostatitis/Chronic Pelvic Pain Syndrome
Published
2007-08-20
How to Cite
1.
Kulovac B, Aganović D, Prcić A, Hadžiosmanović O. Management of Chronic Nonbacterial Prostatitis/Chronic Pelvic Pain Syndrome. Bosn J of Basic Med Sci [Internet]. 2007Aug.20 [cited 2021Jul.29];7(3):245-9. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/3053
Section
Translational and Clinical Research