Clinical Outcome and Hormone Profiles Before and After Laparoscopic Electroincision of the Ovaries in Women With Polycystic Ovary Syndrome

  • Zulfo Godinjak Gynecology and Obstetrics Hospital, University of Sarajevo Clinics Centre
  • Ranka Javorić Institute of Clinical Chemistry and Biochemistry Sarajevo, Laboratory of Endocrinology II, University of Sarajevo Clinics Centre
Keywords: aparoscopic electroincision of ovary, polycystic ovary syndrome, hormone profiles

Abstract

The aim of study was to evaluate clinical outcome and hormone profiles of laparoscopic elec-troincision of the ovaries in women with polycystic ovary syndrome (PCOS) before and after treatment. Forty five clomiphene-citrate resistant women with polycystic ovary syndrome underwent laparoscopic electroincision of the ovaries. Serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T), androstenedione, 17 OH progesterone and beta endorphins were recorded before and 24 hours after the treatment. Clinical and reproductive outcome and hormone profiles were analyzed. Patients were observed during 12 months period. Laparoscopic electroincision of the ovaries was successfully performed without complications in all patients. LH/FSH ratio was 1,66 24 hours after treatment. Serum levels of T, androstenedione, 17 OH progesterone, and beta endorphins were significantly reduced 24 hours after laparoscopic electroincision of the ovaries. In follow-up period 87% of patients were recorded to have regular menstrual cycles and 61% pregnancy rate was achieved spontaneously. Laparoscopic electroincision of the ovaries is an effective treatment in clomiphene-citrate resistant women with polycystic ovary syndrome. The high pregnancy rate of the procedure offers a promising management for patients with polycystic ovary syndrome.

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Clinical Outcome and Hormone Profiles Before and After Laparoscopic Electroincision of the Ovaries in Women With Polycystic Ovary Syndrome
Published
2007-05-20
How to Cite
1.
Godinjak Z, Javorić R. Clinical Outcome and Hormone Profiles Before and After Laparoscopic Electroincision of the Ovaries in Women With Polycystic Ovary Syndrome. Bosn J of Basic Med Sci [Internet]. 2007May20 [cited 2020Oct.1];7(2):173-8. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/3076
Section
Translational and Clinical Research