Comparison of confirmed and probable COVID-19 patients in the intensive care unit during the normalization period

  • Fatma İrem Yeşiler Department of Anesthesiology and Critical Care, Başkent University Faculty of Medicine, Ankara, Turkey https://orcid.org/0000-0002-0612-8481
  • Mesher Çapras Department of Anesthesiology and Critical Care Unit, Baskent University Faculty of Medicine, Ankara, Turkey
  • Emre Kandemir Department of Anesthesiology and Critical Care Unit, Baskent University Faculty of Medicine, Ankara, Turkey
  • Helin Şahintürk Department of Anesthesiology and Critical Care Unit, Baskent University Faculty of Medicine, Ankara, Turkey
  • Ender Gedik Department of Anesthesiology and Critical Care Unit, Baskent University Faculty of Medicine, Ankara, Turkey
  • Pınar Zeyneloğlu Department of Anesthesiology and Critical Care Unit, Baskent University Faculty of Medicine, Ankara, Turkey
Keywords: COVID-19, SARS-CoV-2, confirmed, probable, intensive care unit, normalization period

Abstract

The decrease in social distance together with the normalization period as of June 1, 2020 in our country caused an increase in the number of COVID 19 patients. Our aim was to compare the demographic features, clinical courses and outcomes of confirmed and probable coronavirus disease 2019 (COVID-19) patients admitted to our intensive care unit (ICU) during the normalization period. Critically ill 128 COVID-19 patients between June 1 - December 2, 2020 were analyzed retrospectively. The mean age was 69.7±15.5y (61.7% male). Sixty-one patients (47.7%) were confirmed. Dyspnea (75.0%) was the most common symptom and hypertension (71.1%) was the most common comorbidity. The mean Acute Physiology and Chronic Health Evaluation System (APACHE II) score; Glasgow Coma Score (GCS); Sequential Organ Failure Assessment (SOFA) scores on ICU admission were 17.4 ± 8.2, 12.3 ± 3.9 and 5.9 ± 3.4, respectively. 101 patients (78.1%) received low flow oxygen, 48 had high flow oxygen therapy (37.5%) and 59 (46.1%) had invasive mechanical ventilation. 53 patients (41.4%) had vasopressor therapy and 30 (23.4%) patients had renal replacement therapy (RRT) due to acute kidney injury (AKI). Confirmed patients were more tachypneic (p=0.005) and more hypoxemic than probable patients (p<0.001). Acute respiratory distress syndrome (ARDS) and AKI were more common in confirmed patients than probable (both p<0.001). Confirmed patients had higher values of hemoglobin, C- reactive protein, fibrinogen, D-dimer than probables (respectively, p=0.028, 0.006, 0.000, 0.019). The overall mortality was higher in confirmed patients (p=0.209, 52.6% vs 47.4%). Complications are more common among confirmed COVID-19 patients admitted to ICU. The mortality rate of confirmed COVID-19 patients admitted to the ICU was found to be higher than probable patients. Mortality of confirmed cases were higher than prediction of APACHE-II scoring system.

Downloads

Download data is not yet available.
Comparison of confirmed and probable COVID-19 patients in the intensive care unit during the normalization period
Published
2021-11-22
How to Cite
1.
Yeşiler F İrem, Çapras M, Kandemir E, Şahintürk H, Gedik E, Zeyneloğlu P. Comparison of confirmed and probable COVID-19 patients in the intensive care unit during the normalization period. Bosn J of Basic Med Sci [Internet]. 2021Nov.22 [cited 2021Dec.6];. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/6657
Section
Translational and Clinical Research