Genetics, Genomics, and Multi-omics

112 Items

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Hypomethylation of the ENPP3 promoter region contributes to the occurrence and development of ovarian endometriosis via the AKT/mTOR/4EBP1 signaling pathway

Yuzhen Qin, Yishuai Li, Yali Hao, Yan Li, Shan Kang

848-856
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Hsa_circ_0023179 modulated the processes of proliferation, apoptosis, and EMT in non-small cell lung cancer cells via the miR-615-5p/CDH3 axis

Qingkui Guo, Min Zheng, Chen Zhu, Bin Wu

155–164
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Hsa_circ_0001492 regulates the hsa-miR-145-5p/ovarian carcinoma immunoreactive antigen domain 2 axis to promote the progression of lung adenocarcinoma

Yuanqiang He, Gang Li, Ran Fu, Yue Li, Ying Wang

940–953
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Glioblastoma induces CAF-like astrocyte activation via the AKT/mTOR–SERPINH1/COL5A1 axis

Jingxian Zhang, Yajia Chen, Hongwu Xu

2737–2754
Genomic correlation, shared loci, and causal link between obesity and diabetic microvascular complications: A genome-wide pleiotropic analysis

Wei Zhang, Qinghua Zhang, Yan Luo, Leilei Ma, Xuejun Wang, Qiao Zheng, Xiaotian Zhang, Shentao Wu, Zhan Li, Yingfei Bi

2197–2208
Genetic risk of alcohol-related liver cirrhosis: Associations of PNPLA3, TM6SF2, and a two-variant polygenic risk score

Branka Nesic, Marina Jelovac, Teodora Karan-Djurasevic, Dusica Vrinic Kalem, Petar Svorcan, Branka Zukic, Ivana Grubisa

1006–1016
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Genetic determinants of lipid metabolism in cardioprotection: From mechanisms to clinical practice

Mia Manojlovic, Diana Mahmoud, Magdalena Pantic, Melaku Taye Amogne

872–884
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Gene polymorphisms of miR-323b and miR-1343 that regulate kininogen L are associated with schizophrenia susceptibility: A preliminary population‑based study

Xiaoyu Liu, Mengdi Jin, Mingjia Yang, Lijuan Yan, Weijiao Zhao, Lizhuo Liu, Hongmin Wang, Yongzhuo Ding, Yanyan Sun, Yanchi Zhang, Qiong Yu

1293–1301
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Fecal DNA SDC2 methylation test for colorectal cancer diagnosis: A systematic review and meta-analysis

Xinxin Liu, Bing Yang, Dongxin Tang
- PROVISIONAL PDF
Exploring the link between environmental chemical exposures and epigenetic modifications in diabetes mellitus: A review

Tasnim R. Matarid, Menatallah Rayan, Ola J. Hussein, Hanan H. Abunada, Zaid H. Maayah, Hesham M. Korashy

2607–2619
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Exploratory genetic analysis in children with autism spectrum disorder and other developmental disorders using whole exome sequencing

Edin Hamzic, Lemana Spahic, Nirvana Pistoljevic, Eldin Dzanko, Sanela Pasic, Lejla Kadric, Fadila Serdarevic, Aida Hajdarpasic

888-896
Exosome miR-4738-3p-mediated regulation of COL1A2 through the NF-κB and inflammation signaling pathway alleviates osteoarthritis low-grade inflammation symptoms

Jun Xu, Kaifeng Zhou, Huijie Gu, Yiming Zhang, Liang Wu, Chong Bian, Zhongyue Huang, Guangnan Chen, Xiangyang Cheng, Xiaofan Yin

520–536
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ERBB4 as a therapeutic target in aortic dissection: Implications for cell-based therapies in vascular regeneration

Yu Shi, Jinjin Meng, Shengqiang Zhang, Shaofeng Yang, Ge Liu, Zhen Wu, Chongwen Shen, Chao Shi

2324–2334
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EPAS1 amplifies asthma pathogenesis through JAK2/STAT3-mediated ferroptosis and inflammation

Lili Liu, Cheng Yang, Yan Li, Hao Zhou, Mei Shi, Tiantian Shi, Weibing Shi

2092–2113
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Enhanced membrane protein production in HEK293T cells via ATF4 gene knockout: A CRISPR-Cas9 mediated approach

Byung-Jo Choi, Ba Reum Kim, Ho Joong Choi, Ok-Hee Kim, Say-June Kim

1961–1971
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ELANE rs17223045C/T and rs3761007G/A variants: Protective factors against COVID-19

José Manuel Fragoso, Gilberto Vargas-Alarcón, Ángel Emmanuel Martínez-Flores, Isela Montufar-Robles, Rosa Elda Barbosa-Cobos, Gustavo Rojas-Velasco, Julian Ramírez-Bello

665–672
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Effect of vascular endothelial growth factor rs35569394 in esophageal cancer and response to chemotherapy

Zishan Wang, Chenwei Li, Xinjian Li, Jianguang Shi, Weijie Wu

271–276
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Downregulation of SIRT1 and GADD45G genes and left atrial fibrosis induced by right ventricular dependent pacing in a complete atrioventricular block pig model

Wei-Chieh Lee, Yu-Sheng Lin, Man-Jing Chen, Wan-Chun Ho, Huang-Chung Chen, Tzu-Hao Chang, Ping-Yen Liu, Mien-Cheng Chen

360–373
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Diagnostic and prognostic value of circulating microRNA-21 in heart failure: A systematic review and meta-analysis

Annisa Salsabilla Dwi Nugrahani, Wynne Widiarti, Roy Novri Ramadhan, Citrawati Dyah Kencono Wungu, Hendri Susilo, Indah Mohd Amin

912–923
Deciphering transcriptional dynamics of cardiac hypertrophy and failure in a chamber-specific manner

Dan Zhang, Jianming Liu, Haiying Xiao, Jun Li, Ling Cao, Guang Li

984–996

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